Integrin alpha 3 Antibody

CAT: 0800-F53345-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
CAT#:0800-F53345-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
CAS Number
9007-83-4
Specifications
Western blot: 1:2000-4000
UniProt
P26006
Host
Rabbit
Reactivity
Human
Immunogen
This Integrin alpha 3 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 165-199 amino acids from the N-terminal region of human ITGA3.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Integrin alpha 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Integrin alpha 3 antibody is available for research use only.
Storage Conditions
Aliquot the Integrin alpha 3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Integrin alpha 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of Integrin alpha 3 antibody at 1:4000 dilution and 1) A431 lysate, 2) HeLa lysate, and 3) PC3 lysate at 1:2000. Expected molecular weight: 119-150 kDa depending on glycosylation level.

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