KDM6A Antibody

CAT: 0800-F53253-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
CAT#:0800-F53253-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
CAS Number
9007-83-4
Specifications
Western blot: 1:2000
UniProt
O15550
Host
Rabbit
Reactivity
Human
Immunogen
This KDM6A antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 797-832 amino acids from the Central region of human KDM6A.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the KDM6A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This KDM6A antibody is available for research use only.
Storage Conditions
Aliquot the KDM6A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the KDM6A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of KDM6A antibody at 1:2000 dilution. Lane 1: human liver lysate; 2: HeLa lysate; Predicted molecular weight ~ 154 kDa.

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