Klf4 Antibody

CAT: 0800-F53108-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
CAT#:0800-F53108-0.4MLSize:0.4 mL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription (By similarity) .
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Flow cytometry: 1:25
UniProt
Q60793
Host
Rabbit
Reactivity
Mouse
Immunogen
This Klf4 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 321-354 amino acids from the central region of mouse Klf4.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Klf4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Klf4 antibody is available for research use only.
Storage Conditions
Aliquot the Klf4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Klf4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of lysate from mouse (1) small intestine and (2) testis tissue lysate using Klf4 antibody at 1:1000. Predicted molecular weight: 50-60 kDa + possible ~75 kDa (phosphorylated form) .

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