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SOX7 Antibody

CAT: 0800-F52990-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
CAT#:0800-F52990-0.08MLSize:0.08 mL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity) . May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity) . Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity) . Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q9BT81
Host
Rabbit
Reactivity
Human
Immunogen
This SOX7 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 319-353 amino acids from the C-terminal region of human SOX7.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SOX7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SOX7 antibody is available for research use only.
Storage Conditions
Aliquot the SOX7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the SOX7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse
Image Legend
Western blot analysis of lysate from 1) HCT116 cell line and 2) human heart tissue using SOX7 antibody at 1:1000. Predicted molecular weight: 42/49 kDa (isoforms 1/2) .
Product Datasheet
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