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Caspase-9 Antibody

CAT: 0800-F50930-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F50930-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Caspase 9 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Immunofluorescence: 1:10-1:50
UniProt
P55211
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 183-211 from the human protein was used as the immunogen for this Caspase-9 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, IF, WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the Caspase-9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Caspase-9 antibody is available for research use only.
Storage Conditions
Aliquot the Caspase-9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Caspase-9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Caspase-9 antibody western blot analysis in 1) human HeLa and 2) mouse L929 lysate

UniProtKB · P55211

Caspase-9

CASP9_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P55211
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CASP9
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CASP-9
EC number
3.4.22.62
Processing
Precursor
Secondary accessions
B4E1A3, O95348, Q53Y70, Q5JRU9, Q5UGI1, Q92852, Q9BQ62, Q9UEQ3, Q9UIJ8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Apoptosis

Molecular function

HydrolaseProteaseThiol protease

PTM

PhosphoproteinUbl conjugationZymogen

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