BACE1 Antibody

CAT: 0800-F50758-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
CAT#:0800-F50758-0.08MLSize:0.08 mL
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Description
Responsible for the proteolytic processing of the amyloid precursor protein (APP) . Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50
UniProt
P56817
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 38-70 from the human protein was used as the immunogen for this BACE1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Store at 4oC for up to one month. For long term, aliquot the BACE1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This BACE1 antibody is available for research use only.
Storage Conditions
Store at 4°C for up to one month. For long term, aliquot the BACE1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the BACE1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Rat, Bovine
Image Legend
IHC analysis of FFPE human brain tissue stained with BACE1 antibody

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