Histamine

Histamine

• CAS Number: 51-45-6
• UNSPSC Description: Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter.
• Target Antigen: Endogenous Metabolite; Histamine Receptor
• Type: Natural Products
• Related Pathways: GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease;Neuronal Signaling
• Applications: Cancer-programmed cell death
• Field of Research: Neurological Disease; Endocrinology; Cancer
• Assay Protocol: https://www.medchemexpress.com/Histamine.html
• Purity: 99.99
• Solubility: H2O : 125 mg/mL (ultrasonic)
• Smiles: NCCC1=CN=CN1
• Molecular Weight: 111.148
• References & Citations: [1]Rizell M, Naredi P, Lindnér P, Hellstrand K, Sarno M, Jansson PA. Histamine pharmacokinetics in tumor and host tissues after bolus-dose administration in the rat. Life Sci. 2002 Jan 11;70(8):969-76. |[2]Okabe S, et al. Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers. Am J Dig Dis. 1977 Aug;22(8):677-84. Adv Sci (Weinh). 2023 Jan 15;e2203869.|Biol Pharm Bull. 2023;46(6):864-868.|bioRxiv. 2024 June 12.|Br J Pharmacol. 2021 Jan 27.|Cancer Cell. 2022 Sep 1;S1535-6108(22)00378-6.|Front Pharmacol. 2019 Nov 15;10:1380.|J Cell Commun Signal. 2022 Oct 25.|Microbiol Spectr. 2023 Jan 31;e0469822.|Mbio. 2022 Aug 24;e0200422.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, stored under nitrogen, away from moisture)
• Clinical Information: Launched