FGFR Antibody

CAT: 0800-F50612-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
CAT#:0800-F50612-0.4MLSize:0.4 mL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P11362
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 441-470 from the human protein was used as the immunogen for this FGFR antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the FGFR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This FGFR antibody is available for research use only.
Storage Conditions
Aliquot the FGFR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the FGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Chicken, Mouse, Rat
Image Legend
Western blot analysis of FGFR antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FGFR1 gene (2) . Predicted molecular weight: 75-160 kDa depending on glycosylation level.

Related Products

CatalogName
V5062SAF-100UGBFGF Antibody / Basic FGF / FGF2
V5062-20UGBFGF Antibody / Basic FGF / FGF2
V5062-100UGBFGF Antibody / Basic FGF / FGF2
F50618-0.4MLFGFR2 Antibody
R31921FGF2 Antibody
R30549FGFR1 Antibody
F53229-0.08MLFGF2 Antibody
F53229-0.4MLFGF2 Antibody
F52700-0.08MLFGFR3 Antibody
F51933-0.08MLFGFR1 Antibody

Alternative Products

CatalogName
C0192-01FGFR-3 Antibody
C20779-01FGFR-5 Antibody
N0266-01FGFR-4 Antibody
GWB-2E61CDFGFR-2, Antibody
GWB-E89BE5FGFR-3, Antibody
GWB-C752F4FGFR-1, Antibody
MBS9232322-01FGFR (Y766) Antibody
abx031862-01FGFR (pY766) Antibody
RA24948-01FGFR-3 Polyclonal Antibody
UB-GEN-12736FGFR-4 Monoclonal Antibody

Popular Products