TSC2 Antibody (phospho-S1420)
CAT:
800-F48541-0.08ML
Size:
0.08 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TSC2 Antibody (phospho-S1420)
- Description: Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.
- CAS Number: 9007-83-4
- UniProt: P49815
- Host: Rabbit
- Immunogen: This phospho-TSC2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS1420 of human TSC2.
- Clonality: Polyclonal
- Isotype: Ig
- Applications: DB, IF, ELISA
- Format: Antigen affinity purified
- Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
- Reconstitution: Aliquot the phospho-TSC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This phospho-TSC2 antibody is available for research use only.