Phospho-TSC2 Antibody (pS1096)

• Description:

  Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

• Specifications:

  Dot blot: 1:500

• UniProt:

  P49815

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This phospho-TSC2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS1096 of human TSC2.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  DB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the phospho-TSC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This phospho-TSC2 antibody is available for research use only.

• Storage Conditions:

  Aliquot the phospho-TSC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the phospho-TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Dot blot analysis of phospho-TSC2 antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.