Products for Research Use Only

BMPR1A Antibody

CAT: 0800-F47727-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F47727-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
On ligand binding, BMPR1A forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4. Positively regulates chondrocyte differentiation through GDF5 interaction (By similarity) . [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Flow Cytometry: 1:10-1:50
UniProt
P36894
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1-30 from the human protein was used as the immunogen for this BMPR1A antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the BMPR1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This BMPR1A antibody is available for research use only.
Storage Conditions
Aliquot the BMPR1A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the BMPR1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of lysate from 1) HeLa, 2) K562, 3) MCF-7 cell line, 4) human liver and 5) mouse liver tissue lysate using BMPR1A antibody at 1:1000. Predicted molecular weight ~60 kDa.
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