AP2 alpha Antibody (TFAP2A, Activator protein 2)

AP2 alpha Antibody (TFAP2A, Activator protein 2)

• Description: Activator protein 2 is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle.
• CAS Number: 9007-83-4
• UniProt: P05549
• Host: Rabbit
• Immunogen: A portion of amino acids 104-133 from the human protein was used as the immunogen for this AP2 antibody.
• Clonality: Polyclonal
• Isotype: Ig
• Applications: WB, ELISA
• Format: Antigen affinity purified
• Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Reconstitution: Aliquot the AP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This AP2 antibody is available for research use only.