Src Antibody

CAT: 0800-F47453-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
CAT#:0800-F47453-0.4MLSize:0.4 mL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Src is a non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy between members of the SRC kinase family, identification of the specific role of each Src kinase is very difficult. Src appears to be one of the primary kinases activated following engagement of receptors and plays a role in the activation of other protein tyrosine kinase (PTK) families. [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:1000
UniProt
P12931
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A portion of amino acids 24-52 from the human protein was used as the immunogen for this Src antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Src antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Src antibody is available for research use only.
Storage Conditions
Aliquot the Src antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Src antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of lysate from (1) A431, (2) RD, (3) mouse NIH3T3, (4) mouse C2C12, and (5) rat PC-12 cell line using Src antibody at 1:1000.

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