Aurora-B Antibody (Aurkb)
CAT:
800-F44415-0.08ML
Size:
0.08 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Aurora-B Antibody (Aurkb)
- Description: Aurkb may be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity). Phosphorylates 'Ser-10' and 'Ser-28' of histone H3 during mitosis. Required for kinetochore localization of BUB1 and SGOL1 (By similarity).
- CAS Number: 9007-83-4
- UniProt: O70126
- Host: Rabbit
- Immunogen: A portion of amino acids 84-111 from the mouse protein was used as the immunogen for this Aurkb antibody.
- Clonality: Polyclonal
- Isotype: Ig
- Applications: WB, ELISA
- Format: Antigen affinity purified
- Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
- Reconstitution: Aliquot the Aurkb antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This Aurkb antibody is available for research use only.