Products for Research Use Only

Fyn Antibody

CAT: 0800-F44219-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F44219-0.08MLSize:0.08 mL
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Description
Implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P39688
Host
Rabbit
Reactivity
Mouse
Immunogen
A portion of amino acids 507-535 from the mouse protein was used as the immunogen for this Fyn antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Fyn antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Fyn antibody is available for research use only.
Storage Conditions
Aliquot the Fyn antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Fyn antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Human, Pig, Rat
Image Legend
Fyn antibody western blot analysis in mouse lung tissue lysate. Predicted molecular weight: ~59 kDa.

UniProtKB · P39688

Tyrosine-protein kinase Fyn

FYN_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P39688
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Fyn
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
2.7.10.2
Processing
—
Secondary accessions
Q3TAT3, Q3U0T5, Q8K2A3
Protein keywords

Technical term

3D-structureReference proteome

Biological process

Adaptive immunityImmunity

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingManganeseMetal-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmMembraneNucleus

Molecular function

Developmental proteinKinaseTransferaseTyrosine-protein kinase

PTM

LipoproteinMyristatePalmitatePhosphoprotein

Disease

Proto-oncogene

Domain

SH2 domainSH3 domain