KLF4 Antibody

• Description :

  KLF4 is a transcription factor which acts as both an activator and repressor. Binds the CACCC core sequence. Binds to multiple sites in the 5'-flanking region of its own gene and can activate its own transcription. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.

• Specifications :

  Western blot: 1:1000, Immunofluorescence: 1:10-1:50, Flow Cytometry: 1:10-1:50

• UniProt :

  O43474

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  A portion of amino acids 394-421 from the human protein was used as the immunogen for this KLF4 antibody.

• Clonality :

  Polyclonal

• Isotype :

  Ig

• Applications :

  IF, FACS, WB, ELISA

• Purity :

  Purified

• Format :

  Purified

• Buffer :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution :

  Aliquot the KLF4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This KLF4 antibody is available for research use only.

• Storage Conditions :

  Aliquot the KLF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  Titration of the KLF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number :

  9007-83-4

• Image Legend :

  KLF4 antibody western blot analysis in (1) A431 and (2) MCF-7 lysate. Predicted molecular weight: 50-60 kDa + possible ~75 kDa (phosphorylated form) .