Oct3/4 Antibody

CAT: 0800-F41526-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
CAT#:0800-F41526-0.08MLSize:0.08 mL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t (6;22) (p21; q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100
UniProt
Q01860
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 265-297 from the human protein was used as the immunogen for this Oct3/4 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the Oct3/4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Oct3/4 antibody is available for research use only.
Storage Conditions
Aliquot the Oct3/4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Oct3/4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Oct3/4 antibody western blot analysis in MDA-MB231 lysate. Predicted molecular weight ~38/30kDa (isoform A/B) .

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