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HIST1H2BD Antibody

CAT: 0800-F40042-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F40042-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Two transcripts that encode the same protein have been identified for this gene, which is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq].
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P58876
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1-30 from the human protein was used as the immunogen for this HIST1H2BD antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the HIST1H2BD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This HIST1H2BD antibody is available for research use only.
Storage Conditions
Aliquot the HIST1H2BD antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the HIST1H2BD antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse, Rat, Bovine
Image Legend
HIST1H2BD antibody western blot analysis in HL-60 lysate.

UniProtKB · P58876

Histone H2B type 1-D

H2B1D_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P58876
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
H2BC5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

PTM

AcetylationADP-ribosylationGlycoproteinHydroxylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Cellular component

ChromosomeNucleosome coreNucleus

Technical term

Direct protein sequencingProteomics identificationReference proteome

Molecular function

DNA-binding

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