MMP-7-IN-3

MMP-7-IN-3

• CAS Number: 2865097-58-9
• UNSPSC Description: MMP-7-IN-3 is a potent and selective inhibitor of MMP-7. MMP-7-IN-3 suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction[1].
• Target Antigen: MMP
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mmp-7-in-3.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=S(N[C@H](C(O)=O)CCC(NCC(N[C@@H](CC1=CC=NC=C1)C(N[C@@H](C(C)(C)C)C(N2[C@@H](CCC2)CC(N)=O)=O)=O)=O)=O)(C3=CC(C(F)(F)F)=C(C=C3)Cl)=O
• Molecular Weight: 818.26
• References & Citations: [1]Abe-Sato K, et al. Structure-Based Optimization and Biological Evaluation of Potent and Selective MMP-7 Inhibitors for Kidney Fibrosis. J Med Chem. 2023 Oct 20.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported