Products for Research Use Only
RegisterLogin

MMP-7-IN-3

CAT: 0804-HY-156430-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-156430-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MMP-7-IN-3 is a potent and selective inhibitor of MMP-7. MMP-7-IN-3 suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction[1].
CAS Number
2865097-58-9
UNSPSC
12352209
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mmp-7-in-3.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(N[C@H](C(O)=O)CCC(NCC(N[C@@H](CC1=CC=NC=C1)C(N[C@@H](C(C)(C)C)C(N2[C@@H](CCC2)CC(N)=O)=O)=O)=O)=O)(C3=CC(C(F)(F)F)=C(C=C3)Cl)=O
Molecular Formula
C34H43ClF3N7O9S
Molecular Weight
818.26
References & Citations
[1]Abe-Sato K, et al. Structure-Based Optimization and Biological Evaluation of Potent and Selective MMP-7 Inhibitors for Kidney Fibrosis. J Med Chem. 2023 Oct 20.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Mmp-7-IN-3
CAS Number2865097-58-9
PubChem CID168719944
IUPAC Name(2S)-5-[[2-[[(2S)-1-[[(2S)-1-[(2S)-2-(2-amino-2-oxoethyl)pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-1-oxo-3-pyridin-4-ylpropan-2-yl]amino]-2-oxoethyl]amino]-2-[[4-chloro-3-(trifluoromethyl)phenyl]sulfonylamino]-5-oxopentanoic acid
Molecular FormulaC34H43ClF3N7O9S
Molecular Weight818.3
XLogP1.9
Topological Polar Surface Area255
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count14
Rotatable Bond Count18
Heavy Atom Count55
Formal Charge0
Complexity1500
SMILES
CC(C)(C)[C@@H](C(=O)N1CCC[C@H]1CC(=O)N)NC(=O)[C@H](CC2=CC=NC=C2)NC(=O)CNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C3=CC(=C(C=C3)Cl)C(F)(F)F
InChI
InChI=1S/C34H43ClF3N7O9S/c1-33(2,3)29(31(50)45-14-4-5-20(45)16-26(39)46)43-30(49)25(15-19-10-12-40-13-11-19)42-28(48)18-41-27(47)9-8-24(32(51)52)44-55(53,54)21-6-7-23(35)22(17-21)34(36,37)38/h6-7,10-13,17,20,24-25,29,44H,4-5,8-9,14-16,18H2,1-3H3,(H2,39,46)(H,41,47)(H,42,48)(H,43,49)(H,51,52)/t20-,24-,25-,29+/m0/s1
InChIKey
ITXQTOBRXFVFDQ-OKEDDIKYSA-N
Chemical Structure
2D Structure
2D structure of Mmp-7-IN-3
CAS: 2865097-58-9
CID: 168719944
Formula: C34H43ClF3N7O9S
MW: 818.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight818.3
XLogP31.9
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count14
Rotatable Bond Count18
Exact Mass817.2483593
Monoisotopic Mass817.2483593
Topological Polar Surface Area255 Ų
Heavy Atom Count55
Formal Charge0
Complexity1500
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-151540-01MMP-7-IN-1
HY-153913-01MMP-9-IN-7
HY-153563-01MMP-7-IN-2
HY-P81117-01MMP-7 Antibody (Rabbit)
HY-P86378-01MMP-7 Antibody (YA6070, Rabbit)
HY-P705615MMP-7, Cynomolgus (CHO, His)
HY-P703938-01MMP-7, Human (HEK293, His)
HY-172088Tubulin/MMP-IN-3
HY-146216MMP-9-IN-3
HY-P700574-01MMP-7, Rat (P. pastoris, His)

Alternative Products

CatalogName
BA8023-5MMP-7-IN-3
A23207-5MMP-7-IN-3 5mg
A23207-1MMP-7-IN-3 1mg
A23207-10MMP-7-IN-3 10mg
402160-01MMP-7
EMk27582Monkey MMP-7 (MMP-7) ELISA Kit
BA8032-1MMP-7-IN-2
344263-01MMP-7 discontinued
C0273-01MMP-7 Antibody
32-6849-5MMP 7 Human

Popular Products