MMP-7-IN-3

• CAS Number:

  2865097-58-9

• UNSPSC Description:

  MMP-7-IN-3 is a potent and selective inhibitor of MMP-7. MMP-7-IN-3 suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction[1].

• Target Antigen:

  MMP

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mmp-7-in-3.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=S(N[C@H](C(O)=O)CCC(NCC(N[C@@H](CC1=CC=NC=C1)C(N[C@@H](C(C)(C)C)C(N2[C@@H](CCC2)CC(N)=O)=O)=O)=O)=O)(C3=CC(C(F)(F)F)=C(C=C3)Cl)=O

• Molecular Weight:

  818.26

• References & Citations:

  [1]Abe-Sato K, et al. Structure-Based Optimization and Biological Evaluation of Potent and Selective MMP-7 Inhibitors for Kidney Fibrosis. J Med Chem. 2023 Oct 20.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported