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VPS45 rabbit pAb

CAT: 0855-ES12347-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES12347-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
Description
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013],
Product Name Alternative
Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45)
UniProt
Q9NRW7
Swiss Prot
Q9NRW7
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human VPS45 AA range: 470-520
Target
VPS45
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Molecular Weight
65kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
65kD
Fragment
IgG
Subcellular Location
Golgi apparatus membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Associated with Golgi/endosomal vesicles and the trans-Golgi network. .
Other Product Names
Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45)
Gene ID (Human)
11311

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