CSF1R-IN-1

CSF1R-IN-1

• CAS Number: 2095849-04-8
• UNSPSC Description: CSF1R-IN-1 is a CSF1R inhibitor with an with an IC50 of 0.5 nM.
• Target Antigen: c-Fms
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/CSF1R-IN-1.html
• Purity: 98.11
• Solubility: DMSO : 83.33 mg/mL (ultrasonic)
• Smiles: CC1=CC=C(NC(C2=CC=CC(C(F)(F)F)=C2)=O)C=C1NC(C3=CC(C4=CN(C)N=C4)=CN=C3)=O
• Molecular Weight: 479.45
• References & Citations: [1]Ramachandran SA, et al. Design, synthesis and optimization of bis-amide derivatives as CSF1R inhibitors. Bioorg Med Chem Lett. 2017 May 15;27(10):2153-2160.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C, 3 years (Powder)
• Clinical Information: No Development Reported