5-BrdU

• Description :

  5-BrdU (BrdU) is a nucleoside analog that competes with thymidine for incorporation into DNA. 5-BrdU is commonly used in the detection of proliferating cells.

• Product Name Alternative :

  BrdU; 5-Bromo-2'-deoxyuridine; BUdR

• UNSPSC :

  12352005

• Hazard Statement :

  H340, H361

• Target :

  DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

• Type :

  Oligonucleotides

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/5-BrdU.html

• Purity :

  99.97

• Solubility :

  DMSO : 250 mg/mL (ultrasonic) |H2O : 2 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O[C@H]1C[C@H](N2C(NC(C(Br)=C2)=O)=O)O[C@@H]1CO

• Molecular Formula :

  C9H11BrN2O5

• Molecular Weight :

  307.10

• Precautions :

  H340, H361

• References & Citations :

  [1]Levkoff LH, et al. Bromodeoxyuridine inhibits cancer cell proliferation in vitro and in vivo. Neoplasia. 2008 Aug;10 (8) :804-16.|[2]Rothaeusler K, et al. Assessment of cell proliferation by 5-bromodeoxyuridine (BrdU) labeling for multicolor flow cytometry. Curr Protoc Cytom. 2007 Apr; Chapter 7:Unit7.31

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Oligonucleotides

• Clinical Information :

  Phase 2

• CAS Number :

  [59-14-3]