PROTAC BRD9-binding moiety 5

• Description :

  PROTAC BRD9-binding moiety 5 is a selective BRD9 binder with an IC50 value of 4.20 μM, can be used for the synthesis of PROTACs. PROTAC BRD9-binding moiety 5 has antiproliferative activity against cancer cells[1].

• UNSPSC :

  12352005

• Target :

  Epigenetic Reader Domain; Ligands for Target Protein for PROTAC

• Type :

  Reference compound

• Related Pathways :

  Epigenetics; PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/protac-brd9-binding-moiety-5.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CCC1=NN=C2C(NC3=CC(NC(C)=O)=CC=C3)=NC4=C(N12)C=CC=C4

• Molecular Formula :

  C19H18N6O

• Molecular Weight :

  346.39

• References & Citations :

  [1]Pierri M, et al. Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders. Bioorg Chem. 2022 Jan;118:105480.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  BRD9

• CAS Number :

  [893633-37-9]