PROTAC BRD9-binding moiety 5

• Description:

  PROTAC BRD9-binding moiety 5 is a selective BRD9 binder with an IC50 value of 4.20 μM, can be used for the synthesis of PROTACs. PROTAC BRD9-binding moiety 5 has antiproliferative activity against cancer cells[1].

• UNSPSC:

  12352005

• Target:

  Epigenetic Reader Domain; Ligands for Target Protein for PROTAC

• Type:

  Reference compound

• Related Pathways:

  Epigenetics; PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-brd9-binding-moiety-5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCC1=NN=C2C(NC3=CC(NC(C)=O)=CC=C3)=NC4=C(N12)C=CC=C4

• Molecular Formula:

  C19H18N6O

• Molecular Weight:

  346.39

• References & Citations:

  [1]Pierri M, et al. Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders. Bioorg Chem. 2022 Jan;118:105480.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  BRD9

• CAS Number:

  893633-37-9