3-Hydroxyterphenyllin

• Description :

  3-Hydroxyterphenyllin is a metabolite of Aspergillus candidus.3-Hydroxyterphenyllin suppresses proliferation and causes cytotoxicity against A2780/CP70 and OVCAR-3 cells. 3-Hydroxyterphenyllin induces S phase arrest and apoptosis. 3-Hydroxyterphenyllin has the potential for the research of ovarian cancer[1][2].

• Product Name Alternative :

  NSC 299113

• UNSPSC :

  12352005

• Target :

  Apoptosis

• Type :

  Natural Products

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/3-hydroxyterphenyllin.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC1=CC=C(C2=CC(OC)=C(C3=CC=C(C(O)=C3)O)C(O)=C2OC)C=C1

• Molecular Formula :

  C20H18O6

• Molecular Weight :

  354.35

• References & Citations :

  [1]Kurobane I, et al. 3-Hydroxyterphenyllin, a new metabolite of Aspergillus candidus. Structure elucidation by H and C nuclear magnetic resonance spectroscopy. J Antibiot (Tokyo) . 1979;32 (6) :559-564. |[2]Wang Y, et al. 3-Hydroxyterphenyllin, a natural fungal metabolite, induces apoptosis and S phase arrest in human ovarian carcinoma cells. Int J Oncol. 2017;50 (4) :1392-1402.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [66163-76-6]