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Braylin

CAT: 0804-HY-N2958Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N2958Size:1 Each
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Description
Braylin, a coumarin, is a potent phosphodiesterase-4 (PDE4) inhibitor and is involved in anti-inflammatory and immunomodulation, which may serve as a potential target for the study of immunoinflammatory diseases[1].
CAS Number
6054-10-0
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/braylin.html
Solubility
10 mM in DMSO
Smiles
COC1=C2C(C=CC(C)(C)O2)=C(O3)C(C=CC3=O)=C1
Molecular Formula
C15H14O4
Molecular Weight
258.27
References & Citations
[1]Renan Fernandes Espírito-Santo, et al. The anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approaches. PLoS One. 2017 Jun 8;12 (6) :e0179174.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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