Products for Research Use Only
RegisterLogin

4″-C18 EGCG

CAT: 0804-HY-168074Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-168074Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
4″-C18 EGCG is a potent inhibitor of α-amylase and α-glucosidase with IC50 values of 3.74 and 0.81 μM, respectively. 4″-C18 EGCG inhibits carbohydrate hydrolases, reduces oxidative stress and inflammation, and exhibits antidiabetic activity. 4″-C18 EGCG also downregulates proinflammatory cytokines and is cytotoxic to primary human peripheral blood mononuclear cells (PBMCs), non-cancer cell lines 3T3-L1, and HEK 293 at 50 μM[1].
UNSPSC
12352005
Target
Amylases; Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/4-c18-egcg.html
Smiles
OC(C(O)=C1)=C(O)C=C1[C@@H](O2)[C@H](OC(C3=CC(O)=C(OCCCCCCCCCCCCCCCCCC)C(O)=C3)=O)CC4=C2C=C(O)C=C4O
Molecular Formula
C40H54O11
Molecular Weight
710.85
References & Citations
[1]Kothari M, et al. Lipophilic derivatives of EGCG as potent α-amylase and α-glucosidase inhibitors ameliorating oxidative stress and inflammation[J]. Bioorganic Chemistry, 2024: 107786.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-150526EGCG-4″-sulfate
HY-N6263-01EGCG Octaacetate
HY-1574445,3',4',3'',4'',5''-6-O-Ethyl-EGCG
HY-164412Phosphatidylcholine (C18:2, C20:4)
HY-141580-01C18 Dihydroceramide
HY-130345-01PAF (C18)
HY-W783254C18 LPA
HY-100355-01C18-Ceramide
HY-W592010-01C18-PEG4-Azide
HY-130345S-01C18-PAF-d4

Alternative Products

CatalogName
T200476-014"-C18 EGCG
T200812-014''-C18 EGCG
T74893-01EGCG-4′′-sulfate
MBS5816827EGCG-4"-sulfate
YLA70057-01(-) -Epigallocatechin-4'-o-methylether gallate 〔 (-) -egcg-4'-o-Me〕
02584-81(-)-Epigallocatechin-4'-O-methylether Gallate 〔 (-)-EGCg-4'-O-Me〕
05168-51(-)-Epigallocatechin 3-(4''-O-Methyl)gallate 〔 (-)-EGCg-4''-O-Me〕
4524/50EGCG
GTR19167255-01EGCG Octaacetate
255227EGCG discontinued

Popular Products