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Arformoterol

CAT: 0804-HY-B0010A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0010A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Arformoterol ((R, R) -Formoterol), the (R, R) -enantiomer of Formoterol, is a long-acting β2-adrenergic receptor (β2-AR) agonist, with a Kd of 2.9 nM. Arformoterol can be used for the research of chronic obstructive pulmonary disease (COPD) [1][2].
CAS Number
67346-49-0
Product Name Alternative
(R, R) -Formoterol
UNSPSC
12352005
Hazard Statement
H332, H351, H361, H370, H372
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/arformoterol.html
Purity
99.96
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC1=CC=C([C@@H](O)CN[C@H](C)CC2=CC=C(OC)C=C2)C=C1NC=O
Molecular Formula
C19H24N2O4
Molecular Weight
344.40
Precautions
H332, H351, H361, H370, H372
References & Citations
[1]Handley DA, et, al. Biological actions of formoterol isomers. Pulm Pharmacol Ther. 2002;15 (2) :135-45.|[2]Cazzola M, et, al. Arformoterol tartrate in the treatment of COPD. Expert Rev Respir Med. 2010 Apr;4 (2) :155-62.|[3]Song W, et, al. Postexposure administration of a {beta}2-agonist decreases chlorine-induced airway hyperreactivity in mice. Am J Respir Cell Mol Biol. 2011 Jul;45 (1) :88-94.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor

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