Melanin Concentrating Hormone, salmon

• UNSPSC Description:

  Melanin Concentrating Hormone, salmon is a 19-amino-acid neuropeptide initially identified in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-concentrating hormone is a ligand for an orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2.

• Target Antigen:

  MCHR1 (GPR24)

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Neurological Disease; Cardiovascular Disease; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/Melanin_Concentrating_Hormone,_salmon.html

• Purity:

  98.40

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)CCC(O)=O)=O)[C@H]3NC([C@]4(N(C([C@H](CCCNC(N)=N)NC([C@H](CC5=CC=C(O)C=C5)NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](C(C)C)NC([C@H](CCSC)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)[C@@H](C)O)=O)CCSC)=O)CCCNC(N)=N)=O)CSSC3)=O)=O)=O)=O)=O)=O)=O)=O)CCC4)[H])=O

• Molecular Weight:

  2099.48

• References & Citations:

  [1]An S, et al. Identification and characterization of a melanin-concentrating hormone receptor. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7576-81.|[2]Della-Zuana O, et al. Acute and chronic administration of melanin-concentrating hormone enhances food intake and body weight in Wistar and Sprague-Dawley rats. Int J Obes Relat Metab Disord. 2002 Oct;26(10):1289-95.|[3]Gomori A, et al. Chronic intracerebroventricular infusion of MCH causes obesity in mice. Melanin-concentrating hormone. Am J Physiol Endocrinol Metab. 2003 Mar;284(3):E583-8. Epub 2002 Nov 26.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  87218-84-6