Products for Research Use Only
RegisterLogin

Adrenocorticotropic hormone

CAT: 0804-HY-106373-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-106373-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Adrenocorticotropic hormone (ACTH; Adrenocorticotrophic hormone) is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone stimulates cortisol secretion from the adrenal cortex via the hypothalamic-pituitary-adrenal (HPA) axis. Adrenocorticotropic hormone regulates cortisol and androgen production. Adrenocorticotropic hormone can promote the development of spermatogenesis. Adrenocorticotropic hormone can relieve acute inflammation in gout models by inhibiting the polarization of macrophages to M1 type, inhibiting ROS and proinflammatory factor production and protecting mitochondrial function. Adrenocorticotropic hormone can be used for the researches of inflammation, endocrinology, metabolic disease, such as gout and nephrotic syndrome[1][2][3][4].
CAS Number
9002-60-2
Product Name Alternative
ACTH; Adrenocorticotrophic hormone
UNSPSC
12352209
Hazard Statement
H317, H332, H334, H361
Target
Androgen Receptor; Interleukin Related; Mitochondrial Metabolism; Reactive Oxygen Species (ROS) ; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/adrenocorticotropic-hormone.html
Purity
99.17
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C([C@@H](N)CO)N[C@H](C(N[C@H](C(N[C@HO=C([C@@H](N)CO)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC5=CC=CC=C5)=O)CCC(O)=O)=O)CC(C)C)=O)CCC4)=O)CC6=CC=CC=C6)=O)C)=O)CCC(O)=O)=O)C)=O)CO)=O)CCC(O)=O)=O)CC(O)=O)=O)CCC(O)=O)=O)C)=O)=O)CC(N)=O)=O)CCC3)=O)CC7=CC=C(O)C=C7)=O)C(C)C)=O)CCCCN)=O)C(C)C)=O)CCC2)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCCN)=O)CCCCN)=O)=O)C(C)C)=O)CCC1)=O)CCCCN)=O)=O)CC8=CNC9=CC=CC=C89)=O)CCCNC(N)=N)=O)CC%10=CC=CC=C%10)=O)CC%11=CNC=N%11)=O)CCC(O)=O)=O)CCSC)=O)CO)=O)CC%12=CC=C(O)C=C%12
Molecular Formula
C207H308N56O58S
Molecular Weight
4541.14
Precautions
H317, H332, H334, H361
References & Citations
[1]Yamamoto R, et al.. Physiology, Adrenocorticotropic Hormone (ACTH) . 2025 Dec 1. In: StatPearls [Internet]. Treasure Island (FL) : StatPearls Publishing; 2025 Jan–.|[2]AbuMadighem A, et al. Adrenocorticotropic hormone and its receptor as a novel testicular system involves in the development of spermatogenesis. Life Sci. 2025 May 1;368:123480.|[3]Xu R, et al. Natural Adrenocorticotropic Hormone (ACTH) Relieves Acute Inflammation in Gout Patients by Changing the Function of Macrophages. J Healthc Eng. 2022 Mar 22;2022:9241835.|[4]Bomback AS, et al. Treatment of nephrotic syndrome with adrenocorticotropic hormone (ACTH) . Discov Med. 2011 Aug;12 (63) :91-6.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
IL-1; IL-6

Related Products

CatalogName
HY-P1500Luteinizing Hormone Releasing Hormone (LH-RH), human
HY-P0243-01Luteinizing Hormone Releasing Hormone (LH-RH), salmon
HY-P2293-01Luteinizing hormone (human)
HY-134400Follicle-stimulating hormone
HY-NP197-01Human follicle stimulating hormone
HY-P3824-01Red pigment-concentrating hormone
HY-P4851Adipokinetic hormone (Manduca sexta)
HY-P3568Adipokinetic hormone (Gryllus bimaculatus)
HY-P1833Egg Laying Hormone, aplysia
HY-P1525-01Melanin Concentrating Hormone, salmon

Alternative Products

CatalogName
MBS142672-01Adrenocorticotropic Hormone
abx265577-01Adrenocorticotropic Hormone Peptide
MBS5815758Adrenocorticotropic hormone TFA
RA21005ACTH (Adrenocorticotropic Hormone)
A10L23Adrenocorticotropic hormone (ACTH)

Popular Products