UG-480

• Description:

  UG-480 is a gemini analog that effectively stabilizes the active VDR conformation. UG-480 has antiproliferative effects in estrogen receptor-positive MCF-7 breast adenocarcinoma cells. UG-480 can be used in cancer research[1].

• UNSPSC:

  12352211

• Target:

  VD/VDR

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ug-480.html

• Smiles:

  CC(CCC[C@@H]([C@@H]1C[C@H]1CCC(C)(C)O)[C@@]2([H])CC[C@]3(/C(CCC[C@]23C)=C/C=C4C[C@H](C[C@@H](C/4=C)O)O)[H])(C)O

• Molecular Formula:

  C34H56O4

• Molecular Weight:

  528.81

• References & Citations:

  [1]Gómez-Bouzó, et al. "Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain." Journal of Medicinal Chemistry (2024) .

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported