UG-480

• Description :

  UG-480 is a gemini analog that effectively stabilizes the active VDR conformation. UG-480 has antiproliferative effects in estrogen receptor-positive MCF-7 breast adenocarcinoma cells. UG-480 can be used in cancer research[1].

• UNSPSC :

  12352211

• Target :

  VD/VDR

• Type :

  Reference compound

• Related Pathways :

  Vitamin D Related/Nuclear Receptor

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ug-480.html

• Smiles :

  CC(CCC[C@@H]([C@@H]1C[C@H]1CCC(C)(C)O)[C@@]2([H])CC[C@]3(/C(CCC[C@]23C)=C/C=C4C[C@H](C[C@@H](C/4=C)O)O)[H])(C)O

• Molecular Formula :

  C34H56O4

• Molecular Weight :

  528.81

• References & Citations :

  [1]Gómez-Bouzó, et al. "Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain." Journal of Medicinal Chemistry (2024) .

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported