UG-650

• Description:

  UG-650 is a non-Gemini analog of UVB1 that combines the structural features of UVB1 and MC 1288. UG-650 can bind to the vitamin D receptor (VDR) and inhibit the proliferation of MCF-7 cells and the migration of MC3T3-E1 cells[1].

• UNSPSC:

  12352211

• Target:

  VD/VDR

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Field of Research:

  Cancer

• Smiles:

  O[C@@H](C[C@H](O)C/1=C)CC1=C\C=C2[C@@](CC[C@]3([H])[C@H](CC(CCC(C)(O)C)=C)C)([H])[C@]3(C)CCC\2

• Molecular Formula:

  C29H46O3

• Molecular Weight:

  442.67

• References & Citations:

  [1]Gómez-Bouzó U, et al. Design, synthesis and biological evaluation of a novel non-Gemini analog of UVB1 and crystal structure of its complex with the vitamin D receptor. Bioorg Chem. 2025 Feb 4;157:108239.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported