Ellipyrone B

• Description:

  Ellipyrone B, an antihyperglycemic γ-pyrone enclosed macrocyclic polyketide, shows inhibition potential against dipeptidyl peptidase-4 (IC50=0.48 mM) [1].

• UNSPSC:

  12352005

• Target:

  Dipeptidyl Peptidase

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/ellipyrone-b.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCOC1C/C=C/C2CC(C=C(C(C(CC(CC(OC(C1)C)=O)O)=O)CCC(C)C)O2)=O

• Molecular Formula:

  C25H38O7

• Molecular Weight:

  450.57

• References & Citations:

  [1]Paulose, S.K., et al. Ellipyrones A-B, from oval bone cuttlefish Sepia elliptica: Antihyperglycemic γ-pyrone enclosed macrocyclic polyketides attenuate dipeptidyl peptidase-4 and carbolytic enzymes. Med Chem Res 31, 462–473 (2022) .

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  DPP-4