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Ellipyrone A

CAT: 0804-HY-N10360Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N10360Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ellipyrone A, a γ-pyrone enclosed macrocyclic poyketide, shows inhibition potential against dipeptidyl peptidase-4 (IC50=0.35 mM) . Ellipyrone A also has anti-carbolytic property against α-glucosidase (IC50=0.74 mM) and α-amylase (IC50=0.59 mM) [1].
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ellipyrone-a.html
Solubility
10 mM in DMSO
Smiles
C/C=C/CC1C(CC(CC(OC(CC(C/C=C/C2CC(C=C1O2)=O)OC(C)=O)CC)=O)O)=O
Molecular Formula
C25H34O8
Molecular Weight
462.53
References & Citations
[1]Paulose, S.K., et al. Ellipyrones A-B, from oval bone cuttlefish Sepia elliptica: Antihyperglycemic γ-pyrone enclosed macrocyclic polyketides attenuate dipeptidyl peptidase-4 and carbolytic enzymes. Med Chem Res 31, 462–473 (2022) .
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
DPP-4

Alternative Products

CatalogName
GTR19220363-01Ellipyrone A
T75493-01Ellipyrone B

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