ATPγS (tetralithium salt)

ATPγS (tetralithium salt)

• CAS Number: 93839-89-5
• UNSPSC Description: ATPγS (tetralithium salt) is a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A[1].
• Target Antigen: Eukaryotic Initiation Factor (eIF)
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: COVID-19-anti-virus
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/atpγs-tetralithium-salt.html
• Purity: 98.0
• Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : 75 mg/mL (ultrasonic)
• Smiles: O[C@H]1[C@@H](O[C@H](COP(OP(OP(O[Li])(O[Li])=S)(O[Li])=O)(O[Li])=O)[C@H]1O)N2C3=C(C(N)=NC=N3)N=C2
• Molecular Weight: 546.98
• References & Citations: [1]Matthew L Peck, et al. Adenosine 5'-O-(3-thio)triphosphate (ATPgammaS) is a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A. RNA. 2003 Oct;9(10):1180-7.|[2]Z Y Wang, et al. Mg2+ and ATP or adenosine 5'-[gamma-thio]-triphosphate (ATP gamma S) enhances intrinsic fluorescence and induces aggregation which increases the activity of spinach Rubisco activase. Biochim Biophys Acta. 1993 Sep 3;1202(1):47-55.|[3]Irina A Kolosova, et al. Protective effect of purinergic agonist ATPgammaS against acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2008 Feb;294(2):L319-24.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported