Netarsudil (dimesylate)
CAT:
804-HY-12798A-04
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Netarsudil (dimesylate)
- Product Name Alternative: AR-13324 (dimesylate)
- CAS Number: 1422144-42-0
- UNSPSC Description: Netarsudil mesylate (AR-13324 mesylate) is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.
- Target Antigen: ROCK
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/Netarsudil_mesylate.html
- Purity: 99.56
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: CC1=CC(C)=C(C(OCC2=CC=C([C@@H](CN)C(NC3=CC(C=CN=C4)=C4C=C3)=O)C=C2)=O)C=C1.CS(=O)(O)=O.CS(=O)(O)=O
- Molecular Weight: 645.74
- References & Citations: [1]Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4.|[2]Levy B, et al. Ocular hypotensive safety and systemic absorption of AR-13324 ophthalmic solution in normal volunteers. Am J Ophthalmol. 2015 May;159(5):980-5.e1.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: Launched