Dde Biotin-PEG4-DBCO

Dde Biotin-PEG4-DBCO

• CAS Number: 1807512-43-1
• UNSPSC Description: Dde Biotin-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Dde Biotin-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dde-biotin-peg4-dbco.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCN/C(CCOCCOCCOCCOCCNC(CCCC[C@H]4[C@](NC5=O)([H])[C@](N5)([H])CS4)=O)=C(C6=O)\C(CC(C)(C)C6)=O
• Molecular Weight: 872.08
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported