Atpenin A5
CAT:
804-HY-126653-01
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Atpenin A5
- CAS Number: 119509-24-9
- UNSPSC Description: Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM), and is an effective mKATP channel agonist and cardioprotective agent[1].
- Target Antigen: Potassium Channel
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel
- Field of Research: Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/atpenin-a5.html
- Purity: 99.94
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C1C(C([C@@H](C)C[C@H](C)[C@@H](Cl)CCl)=O)=C(O)C(OC)=C(OC)N1
- Molecular Weight: 366.24
- References & Citations: [1]Andrew P Wojtovich, et al. The complex II inhibitor atpenin A5 protects against cardiac ischemia-reperfusion injury via activation of mitochondrial KATP channels. Basic Res Cardiol. 2009 Mar;104(2):121-9.|[2]Jiyoung Bae, et al. Malonate Promotes Adult Cardiomyocyte Proliferation and Heart Regeneration. Circulation. 2021 May 18;143(20):1973-1986.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported