Bergamottin (Standard)
CAT:
804-HY-N2194R
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Bergamottin (Standard)
- CAS Number: 7380-40-7
- UNSPSC Description: Bergamottin (Standard) is the analytical standard of Bergamottin. This product is intended for research and analytical applications. Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM.
- Target Antigen: Cytochrome P450
- Type: Reference Standards
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/bergamottin-standard.html
- Smiles: O=C1C=CC2=C(OC/C=C(C)/CC/C=C(C)/C)C3=C(OC=C3)C=C2O1
- Molecular Weight: 338.40
- References & Citations: [1]Olguín-Reyes S, et al. Bergamottin is a competitive inhibitor of CYP1A1 and is antimutagenic in the Ames test. Food Chem Toxicol. 2012 Sep;50(9):3094-9.|[2]Wu HJ, et al. Bergamottin isolated from Citrus bergamia exerts in vitro and in vivo antitumor activity in lung adenocarcinoma through the induction of apoptosis, cell cycle arrest, mitochondrial membrane potential loss and inhibition of cell migration and invasion. Oncol Rep. 2016 Jul;36(1):324-32.
- Shipping Conditions: Room temperature