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Cintirorgon (sodium)

CAT: 0804-HY-104037ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-104037ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cintirorgon sodium is a first-in-class, selective and orally bioavailable RORγ agonist. Cintirorgon sodium (LYC-55716) modulates gene expression of RORγ expressing T lymphocyte immune cells, resulting in enhanced effector function, as well as decreased immunosuppression, resulting in decreased tumor growth, and improved survival[1][2].
CAS Number
2055538-47-9
Product Name Alternative
LYC-55716 (sodium)
UNSPSC
12352005
Target
ROR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cintirorgon-sodium.html
Smiles
O=C(O[Na])C(C)(C)C[C@@H]1OC2=CC=C(C3=CC(F)=CC(OC(F)F)=C3)C=C2N(S(=O)(C4=CC=CC(C(F)(F)F)=C4)=O)C1
Molecular Formula
C27H22F6NNaO6S
Molecular Weight
625.51
References & Citations
[1]Lycera Announces Initiation of Phase 1/2a Study ARGON of Immuno-Oncology Candidate LYC-55716 in Patients with Advanced Solid Tumors. Jan 04, 2017.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2