NMDAR2B Recombinant Rabbit Monoclonal Antibody [PSH05-46]

NMDAR2B Recombinant Rabbit Monoclonal Antibody [PSH05-46]

• Description: Glutamate [NMDA] receptor subunit epsilon-2, also known as N-methyl D-aspartate receptor subtype 2B (NMDAR2B or NR2B), is a protein that in humans is encoded by the GRIN2B gene. NR2B has been associated with age- and visual-experience-dependent plasticity in the neocortex of rats, where an increased NR2B/NR2A ratio correlates directly with the stronger excitatory LTP in young animals. This is thought to contribute to experience-dependent refinement of developing cortical circuits. Engineered to overexpress GRIN2B in their brains, mice and rats exhibit improved mental function. The "Doogie" mouse performed twice as well on one learning test.
• Product Name Alternative: AW490526 antibody EIEE27 antibody Glutamate [NMDA] receptor subunit epsilon 2 antibody Glutamate [NMDA] receptor subunit epsilon-2 antibody Glutamate Receptor Ionotropic N Methyl D Aspartate 2B antibody Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B antibody Glutamate receptor ionotropic NMDA2B antibody Glutamate receptor subunit epsilon 2 antibody Glutamate receptor, ionotropic, NMDA2B (epsilon 2) antibody GRIN 2B antibody GRIN2B antibody hNR 3 antibody hNR3 antibody MGC142178 antibody MGC142180 antibody MRD6 antibody N methyl D asparate receptor channel subunit epsilon 2 antibody N methyl D aspartate receptor subtype 2B antibody N methyl D aspartate receptor subunit 2B antibody N methyl D aspartate receptor subunit 3 antibody N-methyl D-aspartate receptor subtype 2B antibody N-methyl-D-aspartate receptor subunit 3 antibody NMDA NR2B antibody NMDA R2B antibody NMDAR2B antibody NMDE2 antibody NMDE2_HUMAN antibody NME2 antibody NR2B antibody NR3 antibody
• Abbreviation: GRIN2B, NMDAR2B
• CAS Number: 9000-83-3
• Swiss Prot: Q13224 Human, Q01097 Mouse, Q00960 Rat
• Cellular Locus: Cell membrane, Postsynaptic cell membrane, Late endosome, Lysosome, Cytoplasm, cytoskeleton.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within human NMDAR2B aa 27-450 / 1,484.
• Isotype: IgG
• Clone: PSH05-46
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IHC-Fr
• Positive Control: Mouse brain tissue lysate, mouse hippocampus tissue lysate, rat brain tissue lysate, rat hippocampus tissue lysate, human brain tissue lysate, mouse hippocampus tissue, rat hippocampus tissue, mouse cerebellum tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IHC-P: 1:2,000-1:8,000 ;IHC-Fr: 1:500
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 166 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes