Basic green 4

• Description :

  Basic green 4 (Malachite green) is a cationic dye that is widely used as a bactericide in aquaculture and is also commonly used in laboratories for the determination of phosphates. Basic green 4 exhibits high cytotoxicity and carcinogenicity to mammalian cells, specifically shown by its IC50 values of 2.03 µM for HEp-2 human laryngeal cells and 13.8 µM for Caco-2 human colorectal adenocarcinoma cells, and it can promote the development of liver tumors. The maximum absorbance wavelength is 621 nm[1][2][3].

• Product Name Alternative :

  Malachite green

• UNSPSC :

  12171500

• Hazard Statement :

  H302, H318, H361, H410

• Target :

  Fluorescent Dye

• Type :

  Dye Reagents

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/basic-green-4.html

• Purity :

  95.88

• Solubility :

  DMSO : 100 mg/mL (ultrasonic) |H2O : 3.85 mg/mL (ultrasonic)

• Smiles :

  C/[N+](C)=C1C=C/C(C=C/1)=C(C2=CC=C(N(C)C)C=C2)\C3=CC=CC=C3.[Cl-]

• Molecular Formula :

  C23H25ClN2

• Molecular Weight :

  364.91

• Precautions :

  H302, H318, H361, H410

• References & Citations :

  [1]Chowdhury. S, et al. Sea shell powder as a new adsorbent to remove Basic Green 4 (Malachite Green) from aqueous solutions: Equilibrium, kinetic and thermodynamic studies. Chemical Engineering Journal, 164 (1), 168–177. |[2]A A Baykov, et al. A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay. Anal Biochem. 1988 Jun;171 (2) :266-70.|[3]Lloyd D. Wright, et al. Effect of Malachite Green and Formalin on the Survival of Largemouth Bass Eggs and Fry. The Progressive Fish-Culturist. 2011 Jan; Pages 155-157.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [569-64-2]