Anti-Hu CD85g FITC

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Anti-Hu CD85g FITC

CAT:

270-1F-164-T100

Size:

100 Tests

Price:

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For price, please contact [email protected].

Anti-Hu CD85g FITC

Background: CD85g / ILT7 (immunoglobulin-like transcript 7) is a cell surface protein that is expressed on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response, such as the TLR-induced interferon production. It associates with gamma subunit of the high-affinity IgE receptor to form a receptor complex which transduces the signal through ITAM-associated downstream molecules. Expression of CD85g is downregulated by interleukin 3.
Specifications: The mouse monoclonal antibody 17G10.2 recognizes an extracellular epitope of CD85g / ILT7, a member of leukocyte immunoglobulin-like receptor family expressed on plasmacytoid dendritic cells, but not on myeloid dendritic cells and other peripheral blood leukocytes.
Certification: RUO
Host: Mouse
Species Reactivity: Human
Target Antigen: CD85g
Isotype: Igg1 κ
Clone: 17G10.2
Applications: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 mL) is sufficient for 100 tests.
Validated Applications: FC
Format: FITC
Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations: *Cao W, Rosen DB, Ito T, Bover L, Bao M, Watanabe G, Yao Z, Zhang L, Lanier LL, Liu YJ: Plasmacytoid dendritic cell-specific receptor ILT7-Fc epsilonRI gamma inhibits Toll-like receptor-induced interferon production. J Exp Med. 2006 Jun 12203(6):1399-405., URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=cao+w+rosen+db+ito+t+bover+l,*Tavano B, Galao RP, Graham DR, Neil SJ, Aquino VN, Fuchs D, Boasso A: Ig-like transcript 7, but not bone marrow stromal cell antigen 2 (also known as HM1.24, tetherin, or CD317), modulates plasmacytoid dendritic cell function in primary human blood leukocytes. J Immunol. 2013 Mar 15190(6):2622-30., URL: https://pubmed.ncbi.nlm.nih.gov/23401591/,*Tavano B, Boasso A: Effect of immunoglobin-like transcript 7 cross-linking on plasmacytoid dendritic cells differentiation into antigen-presenting cells. PLoS One. 2014 Feb 199(2):e89414., URL: http://www.ncbi.nlm.nih.gov/pubmed/24586760 ,
Storage Conditions: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

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Cat	Name
1F-164-T100	Anti-Hu CD85g FITC
1P-164-T100	Anti-Hu CD85g PE
1P-164-T025	Anti-Hu CD85g PE
1A-164-T100	Anti-Hu CD85g APC
11-164-C025	Anti-Hu CD85g Purified
11-164-C100	Anti-Hu CD85g Purified
12-164-C100	Anti-Hu CD85g Purified Low Endotoxin
1F-326-C025	Anti-Hu IgE FITC
1F-142-T100	Anti-Hu IgD FITC
1F-136-T025	Anti-Hu CD157 FITC