Anti-Hu CD157 FITC

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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MBS520528-01	Anti-Mouse CD157 (CD157), FITC, (clone KT157), (Rat IgG2c)

Anti-Hu CD157 FITC

CAT:

270-1F-136-T100

Size:

100 Tests

Price:

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For price, please contact [email protected].

Anti-Hu CD157 FITC

Background: CD157 (cADPr hydrolase 2) is a GPI-anchored ectoenzyme possessing ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activity. It uses NAD and cADP-ribose as substrates. CD157 is expressed on granulocytes, monocytes, macrophages, follicular dendritic cells, bone marrow stromal cells and human umbilical cord vein endothelial cells. In case of rheumatoid arthritis is expression is often higher and it is also differentially expressed in the myeloid leukemias. It may also have a signaling role.
Specifications: The mouse monoclonal antibody SY11B5 recognizes CD157, an approximately 45 kDa GPI-anchored extracellular protein expressed mainly on monocytes, macrophages, granulocytes and bone marrow stromal cells.
Certification: RUO
Host: Mouse
Species Reactivity: Non-human primates, Human
Immunogen: Human CD157
Target Antigen: CD157
Isotype: Igg1 κ
Clone: SY11B5
Applications: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 mL) is sufficient for 100 tests.
Validated Applications: FC
Format: FITC
Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations: *Arriga R, Caratelli S, Coppola A, Spagnoli GC, Venditti A, Amadori S, Lanzilli G, Lauro D, Palomba P, Sconocchia T, Del Principe MI, Maurillo L, Buccisano F, Capuani B, Ferrone S, Sconocchia G: Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage. , URL: https://www.ncbi.nlm.nih.gov/pubmed/26655503,*Correia RP, Bento LC, Bortolucci AC, Alexandre AM, Vaz AD, Schimidell D, Pedro EC, Perin FS, Nozawa ST, Mendes CE, Barroso RS, Bacal NS: Technical advances in flow cytometry-based diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria. Einstein (Sao Paulo). 2016 Jul-Sep14(3):366-373., URL: https://www.ncbi.nlm.nih.gov/pubmed/27759825 ,*Sutherland DR, Richards SJ, Ortiz F, Nayyar R, Benko M, Marinov I, Illingworth A: CD71 improves delineation of PNH type III, PNH type II, and normal immature RBCS in patients with paroxysmal nocturnal hemoglobinuria. Cytometry B Clin Cytom. 2019 Nov 8. doi: 10.1002/cyto.b.21853. , URL: https://www.ncbi.nlm.nih.gov/pubmed/31705743,*Sutherland DR, Illingworth A, Marinov I, Ortiz F, Andreasen J, Payne D, Wallace PK, Keeney M: ICCS/ESCCA consensus guidelines to detect GPI-deficient cells in paroxysmal nocturnal hemoglobinuria (PNH) and related disorders part 2 - reagent selection and assay optimization for high-sensitivity testing. Cytometry B Clin Cytom. 2018 Jan94(1):23-48., URL: https://www.ncbi.nlm.nih.gov/pubmed/29236353,
Storage Conditions: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

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Cat	Name
1F-136-T100	Anti-Hu CD157 FITC
1F-136-T025	Anti-Hu CD157 FITC
1P-136-T100	Anti-Hu CD157 PE
11-136-C025	Anti-Hu CD157 Purified
1A-136-T025	Anti-Hu CD157 APC
11-136-C100	Anti-Hu CD157 Purified
1A-136-T100	Anti-Hu CD157 APC
1P-136-T025	Anti-Hu CD157 PE
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1F-151-T100	Anti-Hu CD49b FITC