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BMP1 (vPairTM) Antibodies

CAT: 0013-GTR18212156Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212156Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to BMP1. BMP1 antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Biorbyt to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody pairs-based assays. The use of a pair of fully characterized vPair antibodies in the same assay can validate signal specificity since vPair antibodies recognize two independent epitopes of the same protein. Different sets of vPair antibodies are developed at Biorbyt to work with specific applications, including antibody pairs arrays, Western blot, IP-Western, ChIP, IHC, and FACS. Bone morphogenetic protein 1 (BMP1) belongs to the peptidase M12A family and cleaves the Cterminal propeptides of procollagen I, II and III. BMP1 induces cartilage and bone formation. BMP1 may also participate in dorsoventral patterning during early development by cleaving chordin (CHRD) . BMP1 is responsible for the proteolytic activation of lysyl oxidase LOX.
Product Name Alternative
Anti Bone morphogenetic protein 1 antibody pairs, anti BMP-1 antibody pairs, anti Mammalian tolloid protein antibody pairs, anti mTld antibody pairs, anti Procollagen C-proteinase antibody pairs, anti PCP antibody pairs
UniProt
P98063
Reactivity
Human, Mouse
Immunogen
N-terminal or the C-terminal region of mouse BMP1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
111
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing either the N-terminal or the C-terminal region of mouse BMP1.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · P98063

Bone morphogenetic protein 1

BMP1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P98063
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Bmp1
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
BMP-1
EC number
3.4.24.19
Processing
Precursor
Secondary accessions
Q6NZM2
Protein keywords

Ligand

CalciumMetal-bindingZinc

Biological process

ChondrogenesisDifferentiationOsteogenesis

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinMethylationZymogen

Molecular function

CytokineDevelopmental proteinGrowth factorHydrolaseMetalloproteaseProtease

Domain

EGF-like domainRepeatSignal

Cellular component

Extracellular matrixGolgi apparatusSecreted

Technical term

Reference proteome

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