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IKZF3 (vPairTM) Antibodies

CAT: 0013-GTR18212066Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212066Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to IKZF3. IKZF3 antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Biorbyt to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody pairs-based assays. The use of a pair of fully characterized vPair antibodies in the same assay can validate signal specificity since vPair antibodies recognize two independent epitopes of the same protein. Different sets of vPair antibodies are developed at Biorbyt to work with specific applications, including antibody pairs arrays, Western blot, IP-Western, ChIP, IHC, and FACS. Zinc finger protein Aiolos (IKZF3) belongs to the Ikaros C2H2-type zinc-finger protein family. IKZF3 is a transcription factor that plays an important role in the regulation of lymphocyte differentiation. IKZF3 plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Additionally, IKZF3 is involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.
Product Name Alternative
Anti Zinc finger protein Aiolos antibody pairs, anti Ikaros family zinc finger protein 3 antibody pairs, anti ZNFN1A3 antibody pairs
UniProt
Q9UKT9
Reactivity
Human
Immunogen
N-terminal or the C-terminal region of human IKZF3
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
58
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing either the N-terminal or the C-terminal region of human IKZF3.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q9UKT9

Zinc finger protein Aiolos

IKZF3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UKT9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IKZF3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DVV5, Q69BL6, Q69BL7, Q69BL8, Q69BL9, Q69BM0, Q69BM1, Q69BM2, Q69BM3, Q69BM5, Q8N574, Q8WWQ9, Q8WWR0, Q8WWR1, Q8WWR2, Q8WWR3
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

B-cell activationTranscriptionTranscription regulation

Cellular component

CytoplasmNucleus

Disease

Disease variant

Molecular function

DNA-binding

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Ligand

Metal-bindingZinc

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger

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