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CAMK2G (C2) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18212128Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212128Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to CAMK2G. Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G) belongs to the protein kinase superfamily, the CAMK Ser/Thr protein kinase family, and the CaMK subfamily. CAMK2G is a calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, CAMK2G is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, CAMK2G may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.
Product Name Alternative
Anti Calcium/calmodulin-dependent protein kinase type II subunit gamma antibody, anti CaM kinase II subunit gamma antibody, anti CaMK-II subunit gamma antibody
UniProt
Q13555
Reactivity
Human
Immunogen
C-terminal region of human CAMK2G
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Neuroscience
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
63
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human CAMK2G.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q13555

Calcium/calmodulin-dependent protein kinase type II subunit gamma

KCC2G_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13555
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CAMK2G
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CaM kinase II subunit gamma, CaMK-II subunit gamma
EC number
2.7.11.17
Processing
—
Secondary accessions
A0A0A0MS52, A0A0A0MT11, O00561, O15378, Q13279, Q13282, Q13556, Q5SQZ3, Q5SQZ4, Q5SWX4, Q7KYX5, Q8N4I3, Q8NIA4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Molecular function

Calmodulin-bindingDevelopmental proteinKinaseSerine/threonine-protein kinaseTransferase

Biological process

DifferentiationNeurogenesis

Disease

Intellectual disability

Cellular component

MembraneSarcoplasmic reticulum

PTM

Phosphoprotein

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