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MALT1 (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18212022Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212022Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to MALT1. MALT1 antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Biorbyt to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody-based assays. The use of a pair of fully characterized vPair antibodies in the same assay can validate signal specificity since vPair antibodies recognize two independent epitopes of the same protein. Different sets of vPair antibodies are developed at Biorbyt to work with specific applications, including antibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS. Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) belongs to the peptidase C14B family and enhances BCL10-induced activation of NF-kappa-B. MALT1 is involved in nuclear export of BCL10. Additionally, MALT1 binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. MALT1 has ubiquitin ligase activity, and MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.
Product Name Alternative
Anti Mucosa-associated lymphoid tissue lymphoma translocation protein 1 antibody, anti MALT lymphoma-associated translocation antibody, anti Paracaspase antibody, anti MLT antibody
UniProt
Q9UDY8
Reactivity
Human
Immunogen
N-terminal region of human MALT1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
92
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing either the N-terminal or the C-terminal region of human MALT1.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q9UDY8

Mucosa-associated lymphoid tissue lymphoma translocation protein 1

MALT1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UDY8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MALT1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.22.-
Processing
—
Secondary accessions
Q9NTB7, Q9ULX4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationDisulfide bondPhosphoprotein

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Cellular component

CytoplasmNucleus

Disease

Disease variant

Molecular function

HydrolaseProtease

Biological process

ImmunityUbl conjugation pathway

Domain

Immunoglobulin domainRepeat

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