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Argireline

CAT: 0804-HY-P0033-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P0033-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Argireline (Acetyl hexapeptide-3) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity[1][2][3].
CAS Number
616204-22-9
Product Name Alternative
Acetyl hexapeptide-3; Acetyl hexapeptide-8
UNSPSC
12352209
Target
Calcium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Argireline.html
Purity
99.77
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
N=C(N)NCCC[C@@H](C(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCSC)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC(C)=O)=O)=O)=O)=O)=O
Molecular Formula
C34H60N14O12S
Molecular Weight
888.99
References & Citations
[1]Blanes-Mira C, et al. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002 Oct;24 (5) :303-10.|[2]Grosicki M, et al. The study of cellular cytotoxicity of argireline - an anti-aging peptide. Acta Biochim Pol. 2014;61 (1) :29-32.|[3]Wang Y, et al. The anti-wrinkle efficacy of Argireline. J Cosmet Laser Ther. 2013 Aug;15 (4) :237-41.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
Phase 3