PAK1 (N2) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210334Size: 100 µLDry Ice: NoHazardous: No

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CAT#:0013-GTR18210334Size:100 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Rabbit polyclonal to PAK1.p21-activated kinase 1 (PAK1) belongs to the protein kinase superfamily, STE Ser/Thr protein kinasefamily and STE20 subfamily. PAK1 can be activated by CDC42 and RAC1, and is likely the GTPaseeffector that links the Rho-related GTPases to the JNK MAP kinase pathway. PAK1 is involved in thedissolution of stress fibers and reorganization of focal complexes, as well as in the regulation ofmicrotubule biogenesis through phosphorylation of TBCB. DVL1 and PAK1 form a ternary complexwith MUSK which is important for MUSK-dependent regulation of AChR clustering during theformation of the neuromuscular junction (NMJ) . The activity of PAK1 is inhibited in cells undergoingapoptosis, potentially due to binding of CDC2L1 and CDC2L2.

Product Name Alternative

Anti-PAK1 antibody, anti-Serine antibody, anti-threonineprotein kinase PAK 1 antibody, anti-AlphaPAK antibody, anti-p21activated kinase 1 antibody, anti-PAK1 antibody, anti-p65PAK Source and antibody

UniProt

Q13153

Reactivity

Human, Mouse

Immunogen

N-terminal region of human PAK1

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Epigenetics & Chromatin

Dilution

WB:1:500-1:2000

Purity

Affinity purification

Molecular Weight

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

Host or Source

Rabbit

Preservative

0.01% NaN3

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PAK1 (N2) Antibody, Rabbit Polyclonal

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